Real-World Implications of Hybrid Close Loop (Hcl) Insulin Delivery System
نویسندگان
چکیده
منابع مشابه
Clinical experience with an implanted closed-loop insulin delivery system.
AIM To report the first clinical experience with a prototype of implanted artificial beta-cell. METHODS The Long-Term Sensor System project assessed the feasibility of glucose control by the combined implantation of a pump for peritoneal insulin delivery and a central intravenous glucose sensor, connected physically by a subcutaneous lead and functionally by PID algorithms. It was performed i...
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Introduction: Sonophoresis has been assessed as a novel approach to create skin permeability and drug delivery using low frequencies of ultrasound waves in the range of 20 kHz to 3 MHz. In this study, a system including seven 40 kHz piezoelectric transducers and an insulin chamber designed by the Medical Physics Research Center has been evaluated on hyperglycemic rabbits. Materials and Methods:...
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The efficacy of a drug in a specific application requires the maintenance of appropriate drug blood level concentration during a prolonged period of time. Controlled release delivery is available for many routes of administration and offers many advantages (as microparticles and nanoparticles) over immediate release delivery. These advantages include reduced dosing frequency, better therapeutic...
متن کاملClosed-Loop Insulin Delivery Using a Subcutaneous Glucose Sensor and Intraperitoneal Insulin Delivery
OBJECTIVE Attempts to build an artificial pancreas by using subcutaneous insulin delivery from a portable pump guided by an subcutaneous glucose sensor have encountered delays and variability of insulin absorption. We tested closed-loop intraperitoneal insulin infusion from an implanted pump driven by an subcutaneous glucose sensor via a proportional-integral-derivative (PID) algorithm. RESEA...
متن کاملHybrid Systems and Real World Computations
In a preface to a book on computational geometry J T Schwartz Sc wrote Till now computer science has been largely combinatorial and symbolic having the manipulation of patterns and tables of data as its principal content In robotics however computer science makes contact with real world geometric and physical phenomena such as compliance of elastic bodies the frictional phenomena that occur whe...
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ژورنال
عنوان ژورنال: Endocrine Practice
سال: 2019
ISSN: 1530-891X
DOI: 10.4158/ep-2018-0515